<font size="2"><font face="trebuchet ms,sans-serif">[Forwarding from Open Medicine. --Peter Suber.]<br></font></font><br><div class="gmail_quote"><br>
FOR IMMEDIATE RELEASE<br>
<br>
Can wikis transform medical publishing?<br>
Open Medicine explores the use of a wiki to update and improve<br>
peer-reviewed systematic reviews.<br>
<br>
OTTAWA, Tuesday, March 1—Today, Open Medicine (<a href="http://openmedicine.ca" target="_blank">openmedicine.ca</a>) is<br>
pleased to announce the publication of a wiki version of a new<br>
systematic review of second-line diabetes drugs. To the best of our<br>
knowledge, Open Medicine is the only peer-reviewed medical journal using<br>
wikis as a publishing platform. “Knowledge is dynamic and a wiki is a<br>
publishing tool that truly reflects that,” says Anita Palepu, MD, editor<br>
of Open Medicine. “Our hope is that this manuscript will evolve as our<br>
knowledge evolves and, ultimately, be improved by contributions directly<br>
from our readers to our authors.”<br>
<br>
The systematic review is authored by a team of researchers affiliated<br>
with the Canadian Agency for Drugs and Technologies in Health (CADTH;<br>
<a href="http://cadth.ca" target="_blank">cadth.ca</a>). It examines the safety and efficacy of second-line type 2<br>
diabetes drugs in patients who cannot achieve optimal control of their<br>
blood sugar using metformin, a first-line treatment, alone. “CADTH is<br>
always looking for innovative ways to share its products with customers.<br>
This is an innovative, collaborative way for readers to not only comment<br>
but contribute to our work using Wiki technology,” says Jane<br>
Farquharson, acting vice-president, Programs, at CADTH.<br>
<br>
According to the Canadian Diabetes Association, nine million Canadians<br>
live with diabetes or prediabetes. By 2020, it is estimated that<br>
diabetes will cost the healthcare system $16.9 billion per year.<br>
Therefore, a clinician’s choice of second-line therapies has important<br>
implications for Canadians. “Given the prevalence of diabetes and<br>
limited dollars in health care budgets, this work is important to<br>
examine the effectiveness of these therapies not only from a cost<br>
perspective but also comparing them with others available to ensure<br>
maximum benefit for the patient,“ says Farquharson.<br>
<br>
Prior to publication as a wiki, this systematic review was peer-reviewed<br>
to ensure it satisfied Open Medicine’s editorial standards. Access to<br>
the wiki version will not be limited to health experts, but readers must<br>
register, state their affiliations and complete a competing-interests<br>
statement before they can contribute. Changes will be monitored by the<br>
journal’s staff and substantive edits will be brought to the attention<br>
of the review authors.<br>
<br>
Systematic reviews can become rapidly outdated as new research is<br>
published. Providing authors and readers with an updated document offers<br>
several advantages, yet biomedical publishers have rarely done so. The<br>
advantages include:<br>
1) Changes to a wiki are publicly available as soon as they are made,<br>
2) Wikis create a centralized document for easy editing,<br>
3) Readers can track the changes that have been made to a document,<br>
provided a form of post-publication peer-review;<br>
For a more thorough discussion of the potential role of wikis in<br>
biomedical publishing, see “Medical research and social media: Can wikis<br>
be used as a publishing platform in medicine?” an editorial by the<br>
editors at Open Medicine published in 2009 when the journal first<br>
piloted a wiki.<br>
<br>
Citation: McIntosh, B., Cameron, C., Singh, S.R., Yu, C., Ahuja, T.,<br>
Welton, N.J., and Dahl, M. (2011) Second-line therapy in patients with<br>
type 2 diabetes inadequately controlled with metformin monotherapy: a<br>
systematic review and mixed-treatment comparison meta-analysis Open Med<br>
5(1):e35-48<br>
<br>
To access the wiki version of this article, visit:<br>
<a href="http://livewiki.openmedicine.ca" target="_blank">http://livewiki.openmedicine.ca</a><br>
<br>
About Open Medicine<br>
Open Medicine is a peer-reviewed, independent, open-access general<br>
medical journal published in Canada. It makes original medical research,<br>
as well as reviews, commentaries and articles on practice, policy and<br>
ethics available freely and immediately to everyone over the Internet.<br>
It is a not-for-profit organization.<br>
<br>
About CADTH<br>
The Canadian Agency for Drugs and Technologies in Health (CADTH) is an<br>
independent, not-for-profit agency funded by Canadian federal,<br>
provincial, and territorial governments to provide credible, impartial<br>
advice and evidence-based information about the effectiveness of drugs<br>
and other health technologies to Canadian health care decision makers.<br>
<br>
For more information, contact:</div><div class="gmail_quote"><br>
Anita Palepu<br>
Editor, Open Medicine<br>
604-682-2344 ext. 63194<br>
<a href="mailto:apalepu@openmedicine.ca">apalepu@openmedicine.ca</a><br>
<br>
Tarek Loubani<br>
Associate Editor, Open Medicine<br>
519-488-6475<br>
<font color="#888888"><a href="mailto:tarek@tarek.org">tarek@tarek.org</a><br>
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